L-Carnitine 1000mg, Weight Management, Supports Healthy Ageing, Boosts Cellular Energy

L-CARNITINE - A Sports Nutrition Perspective

L-Carnitine is a nitrogenous compound naturally found in human skeletal muscle, heart, liver, kidneys and plasma. An average human body contains 20-25g of L-Carnitine, of which over 95% is in skeletal muscles. Carnitine exists in two isomeric forms: L-Carnitine and D-Carnitine, of which L-Carnitine is the physiological active form2. L-Carnitine is a vitamin-like nutrient essential for energy production and fat metabolism. It is used by athletes as an ergogenic aid. Supplementing diet with L-Carnitine increases maximal aerobic power, and promotes glycogen sparing in the course of prolonged exercise. Supplementation of L-Carnitine raises the performance of submaximal exercise and resistance to fatigue. L-Carnitine is present in foods, especially red meat and some dairy foods. Animal products are generally rich sources of Carnitine, while plant foods contain considerably lower levels.

Why is L-Carnitine Supplementation Important?

Although, Carnitine is both biosynthesized and supplied in the diet, there is a need for supplementary Carnitine in some conditions:

  • In competitive athletes, intensive endurance efforts (cycling stage races, repeated long-distance runs, etc.) cause a clearly detectable L-Carnitine deficiency in the muscles. Supplementation can have a positive effect on athletic exercise capacity and can help to maintain fitness, enhance detoxification and aid faster recovery.

  • An unbalanced diet with a low intake of L-Carnitine and/or of one of its precursors often leads to a deficiency in L-Carnitine. It is evident that some vegetarian competitive athletes are Carnitine deficient.

  • Individuals with different physiological conditions (fasting, malnutrition, obesity, infertility in males, dialysis patients, muscle diseases, and hospitalised patients receiving total parental nutrition), may need supplementary L-Carnitine.

What are the Benefits of L-Carnitine Supplementation in Athletes?

L-Carnitine acts as an ergogenic and anti-catabolic agent for sports performance in athletes. Its supplementation can be benefited as follows:

  • 1. Increased utilisation of free fatty acids for energy for increase muscle and heart energy in endurance sports (ergogenic aid)
  • 2. Increased 'Glycogen Sparing' effect in endurance athletes, may provide protection for muscle glycogen stores, which are at risk during periods of increased exercise (anti-catabolic)
  • 3. Reduced lactic acid concentration in muscle leads to a delay in the onset of muscular fatigue and cramps
  • 4. Increased peripheral blood supply provides more oxygen absorption and leads to more energy production in aerobic exercise
  • 5. Increased BCAA metabolism to yield more energy and prodcution of glucose
  • 6. Enhanced removal of ammonia and its detoxification
  • 7. Increased protection to immune system and improved membrane stability during intense physical exercise

1-2 capsules should be taken approximately 30 minutes prior to training. For additional effect take one additional capsule in the morning and at night.

Biochemical Role of L-Carnitine

L-Carnitine possesses following different biochemical functions, which are very important for athletic performance.

A. Creation of metabolic energy.
The primary function of Carnitine in the body is to facilitate the burning of fatty acids for metabolic energy. Since, L-Carnitine involves in energy production and utilisation, it can be considered an ergogenic aid for athletes. L-Carnitine supplementation may protect endurance athlete carbohydrate stores, which are at risk during periods of increased exercise.

B. Carbohydrate Metabolism
Although Carnitine is famous for its fat-burning properties, growing evidence indicates that it is also important in carbohydrate metabolism. It is evident that there is a strong correlation between muscle Carnitine and the activity of the Krebs cycle, a pivotal cycle in carbohydrate metabolism .Carnitine concentration in muscle is found to be directly proportional to muscle glycogen stores.

C. Lactate Clearance
Intensive, acute exercise leads to lactate accumulation and an associated drop in serum pH. High levels of lactic acid increase the acidity of blood and tissues, lead to fatigue and decrease in ATP production. Supplementation may be useful in intense physical exercise to improve performance by clearing extra lactic acid from blood and tissues.

D. Peripheral Blood Supply
L-Carnitine shows a demonstrable increase in peripheral blood supply and capillary dilatation. This can lead to more oxygen absorption and substrate turn over, especially during intense execise.

E. Branched Chain Amino Acid (BCAA) Metabolism
Carnitine levels are linked to the metabolism of BCAAs, considered the most important amino acids for sports performance.The liver for further oxidation to yield energy takes up these Carnitine complexes.

F. Ammonia Detoxification
Ammonia, a by-product of protein degradation, is a recognised factor in exercise-induced fatigue, and is toxic at low amounts. Carnitine works to lower ammonia levels by increasing its incorporation into urea, which is subsequently excreted in the urine. Carnitine supplementation may have a protective effect against ammonia poisoning caused due to intense work-outs.
L-Carnitine also protects the immune system and stabilises membrane during intense physical exercise . More recently, studies have shown that Carnitine act as antioxidants.

Average Values per Capsule

% RDA

L-Carnitine1000 mg**